Cortisol sulfotransferase explained

cortisol sulfotransferase
Ec Number:2.8.2.18
Cas Number:71427-08-2
Go Code:0047785

In enzymology, a cortisol sulfotransferase is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + cortisol

\rightleftharpoons

adenosine 3',5'-bisphosphate + cortisol 21-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and cortisol, whereas its two products are adenosine 3',5'-bisphosphate and cortisol 21-sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase. Other names in common use include glucocorticosteroid sulfotransferase, and glucocorticoid sulfotransferase.

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