Coptisine Explained

Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis),[1] greater celandine, and opium.[2] Famous for the bitter taste that it produces, it is used in Chinese herbal medicine along with the related compound berberine for digestive disorders caused by bacterial infections.[3]

Notes and References

  1. Chen J, Wang F, Liu J, Lee FS, Wang X, Yang H . Analysis of alkaloids in Coptis chinensis Franch by accelerated solvent extraction combined with ultra performance liquid chromatographic analysis with photodiode array and tandem mass spectrometry detections . Analytica Chimica Acta . 613 . 2 . 184–95 . April 2008 . 18395058 . 10.1016/j.aca.2008.02.060 .
  2. 198–201 . 10.1038/189198a0 . Distribution of Certain Poppy-Fumaria Alkaloids and a Possible Link with the Incidence of Glaucoma . 1961 . Hakim . Sohrab A. E. . Mijović . Valerie . Walker . James . Nature . 189 . 4760 . 13710637.
  3. Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y . Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations . Journal of Ethnopharmacology . 126 . 1 . 5–17 . October 2009 . 19686830 . 10.1016/j.jep.2009.08.009 . 10722/127599 . free .

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