| Symbol: | Cu2_monooxygen |
| Copper type II ascorbate-dependent monooxygenase, N-terminal domain | |
| Pfam: | PF01082 |
| Interpro: | IPR000323 |
| Prosite: | PDOC00080 |
| Scop: | 1phm |
| Symbol: | Cu2_monoox_C |
| Copper type II ascorbate-dependent monooxygenase, C-terminal domain | |
| Pfam: | PF03712 |
| Prosite: | PDOC00080 |
| Scop: | 1phm |
In molecular biology, the copper type II ascorbate-dependent monooxygenases are a class of enzymes that require copper as a cofactor and which use ascorbate as an electron donor. This family contains two related enzymes, dopamine beta-monooxygenase and peptidylglycine alpha-amidating monooxygenase . There are a few regions of sequence similarities between these two enzymes, two of these regions contain clusters of conserved histidine residues which are most probably involved in binding copper.[1]