Clofibric acid explained

Clofibric acid is a biologically active metabolite of the lipid-lowering drugs clofibrate, etofibrate and ^[1] with the molecular formula C₁₀H₁₁ClO₃. It has been found in the environment following use of these drugs, for example in Swiss lakes and the North Sea.^{[2] [3]}

Some derivatives of clofibric acid are in a drug class called fibrates.

See also

• Phenoxy herbicides to which the compound is chemically related

Notes and References

1. 10.1016/j.jhazmat.2012.09.029 . Biodegradation of clofibric acid and identification of its metabolites . 2012 . Salgado . R. . Oehmen . A. . Carvalho . G. . Noronha . J.P. . Reis . M.A.M. . Journal of Hazardous Materials . 241-242 . 182–189 . 23062606 .
2. Photochemical fate of pharmaceuticals in the environment: Naproxen, diclofenac, clofibric acid, and ibuprofen. Aquatic Sciences . 65. 4. 342–351. 10.1007/s00027-003-0671-8. 2003. Packer. Jennifer L. Werner. Jeffrey J. Latch. Douglas E. McNeill. Kristopher. Arnold. William A. 24063392.
3. Occurrence of the Pharmaceutical Drug Clofibric Acid and the Herbicide Mecoprop in Various Swiss Lakes and in the North Sea. Environmental Science & Technology. 32. 188–192. 10.1021/es9705811. 1998. Buser. Hans-Rudolf. Müller. Markus D. Theobald. Norbert. 1. 1998EnST...32..188B.