Clitocine Explained

Clitocine is a mushroom nucleoside isolate[1] with anticancer activity in vitro.[2] [3] [4]

Notes and References

  1. Kubo . Isao . Kim . Mujo . Wood . William F. . Naoki . Hideo . 1986 . Clitocine, A New Insecticidal Nucleoside From The Mushroom Clitocybe inversa . Tetrahedron Letters . 27 . 36 . 4277–4280 . 10.1016/S0040-4039(00)94251-5.
  2. Anti-proliferative effect of clitocine from the mushroom Leucopaxillus giganteus on human cervical cancer HeLa cells by inducing apoptosis. 18222036 . 10.1016/j.canlet.2007.12.013 . 262. 2. April 2008. 190–200. Ren . Gang . Zhao . Yun-Peng . Yang . Lu . Fu . Cheng-Xin . Cancer Letters .
  3. Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line. 22927901 . 10.1371/journal.pone.0040720 . 3425549. 7. 8. 2012. PLOS ONE. e40720. Sun . Jianguo . Yeung . Chilam Au . Co . Ngai Na . Tsang . Tsun Yee . Yau . Esmond . Luo . Kewang . Wu . Ping . Wa . Judy Chan Yuet . Fung . Kwok-Pui . Kwok . Tim-Tak . Liu . Feiyan . 2012PLoSO...740720S . free .
  4. Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo. 24563182 . 10.1007/s10495-014-0969-0 . 19. 5. May 2014. Apoptosis. 871–82. Sun . Jian-guo . Li . Hua . Li . Xia . Zeng . Xueli . Wu . Ping . Fung . Kwok-Pui . Liu . Fei-yan . 14746593 .

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