Citrate CoA-transferase explained

citrate CoA-transferase
Ec Number:	2.8.3.10
Cas Number:	65187-14-6
Go Code:	0008814

In enzymology, a citrate CoA-transferase is an enzyme that catalyzes the following chemical reaction:

acetyl-CoA + citrate

\rightleftharpoons acetate + (3S)-citryl-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and citrate, whereas its two products are acetate and (3S)-citryl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:citrate CoA-transferase. This enzyme participates in citrate cycle (tca cycle).

References

• Dimroth P, Loyal R, Eggerer H . 1977 . Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate . Eur. J. Biochem. . 80 . 479 - 88 . 336371 . 10.1111/j.1432-1033.1977.tb11903.x . 2 . free .