Cis-2-Decenoic acid explained

cis-2-Decenoic acid is an unsaturated fatty acid. It is a colorless oil.

Preparation and occurrence

The compound can be prepared from 1-iodonon-1-ene by lithium halogen exchange followed by carbonation.[1]

cis-2-Decenoic acid is produced by Pseudomonas aeruginosa.[2] It may have potential in fighting biofilm implied in infectious diseases[3] that are present in more than 60%[4] of Hospital-acquired infection.

Notes and References

  1. 10.1055/s-1976-25384. Stereospecific Syntheses of Alkenyllithium Reagents from Alkenyl Iodides. 1976. Cahiez. G.. Bernard. D.. Normant. J. F.. Synthesis. 1976. 4. 245–248. 95870283 .
  2. 19074399. 2009. Davies. DG. Marques. CN. A fatty acid messenger is responsible for inducing dispersion in microbial biofilms. 191. 5. 1393–403. 10.1128/JB.01214-08. 2648214. Journal of Bacteriology.
  3. 4695811 . 26610524 . 10.3390/ph8040816 . 8 . 4 . Control of Biofilms with the Fatty Acid Signaling Molecule cis-2-Decenoic Acid . Pharmaceuticals . 816–35 . Marques . CN . Davies . DG . Sauer . K. 2015 . free .
  4. 2706312 . 18366134 . 10.1002/bit.21838 . 100 . 1 . Medical biofilms . 2008 . Biotechnol. Bioeng. . 1–18 . Bryers . JD.

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