Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase explained
| cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase |
| Ec Number: | 1.3.1.56 |
| Go Code: | 0018509 |
In enzymology, a cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase is an enzyme that catalyzes the chemical reaction
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH + H
+Thus, the two substrates of this enzyme are cis-3-phenylcyclohexa-3,5-diene-1,2-diol and NAD+, whereas its 3 products are biphenyl-2,3-diol, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase. This enzyme is also called 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase. This enzyme participates in biphenyl degradation.
References
- Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D . 1996 . Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB) . Appl. Environ. Microbiol. . 62 . 2710 - 5 . 8702262 . 8 . 168055 .
- Takagi M, Yano K . 1994 . Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls . Biochem. Biophys. Res. Commun. . 202 . 850 - 6 . 8048958 . 10.1006/bbrc.1994.2008 . 2 .
- Hofer B, Eltis LD, Dowling DN, Timmis KN . 1993 . Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation . Gene . 130 . 47 - 55 . 8344527 . 10.1016/0378-1119(93)90345-4 . 1 .
