Cinnamyl-alcohol dehydrogenase explained
| cinnamyl-alcohol dehydrogenase |
| Ec Number: | 1.1.1.195 |
| Cas Number: | 55467-36-2 |
| Go Code: | 0045551 |
In enzymology, a cinnamyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reaction
cinnamyl alcohol + NADP+
cinnamaldehyde + NADPH + H
+Thus, the two substrates of this enzyme are cinnamyl alcohol and NADP+, whereas its 3 products are cinnamaldehyde, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cinnamyl-alcohol:NADP+ oxidoreductase. Other names in common use include cinnamyl alcohol dehydrogenase, and CAD. This enzyme participates in phenylpropanoid biosynthesis.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes,,, and .
References
- Sarni F, Grand C, Boudet AM . 1984 . Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana) . Eur. J. Biochem. . 139 . 259 - 65 . 6365550 . 10.1111/j.1432-1033.1984.tb08002.x . 2 . free .
- Wyrambik D, Grisebach H . 1975 . Purification and properties of isoenzymes of cinnamyl-alcohol dehydrogenase from soybean-cell-suspension cultures . Eur. J. Biochem. . 59 . 9 - 15 . 1250 . 10.1111/j.1432-1033.1975.tb02418.x . 1 . free .
- Wyrambik D, Grisebach H . 1979 . Enzymic synthesis of lignin precursors. Further studies on cinnamyl-alcohol dehydrogenase from soybean-cell-suspension cultures . Eur. J. Biochem. . 97 . 503 - 9 . 572771 . 10.1111/j.1432-1033.1979.tb13138.x . 2 . free .
