Cianopramine Explained

Cianopramine (INN) (developmental code name Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor^[1] and weak serotonin receptor antagonist.^{[2] [3]} It was investigated for the treatment of depression but was never marketed.

See also

• Clomipramine
• Cyanodothiepin
• Cyamemazine

Notes and References

1. Kenny M, Lenehan TJ, Lambe R, Darragh A, Brick I, Omer LM . Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers . Psychopharmacology . 1983 . 79 . 4 . 304–7 . 6407042 . 10.1007/bf00433406 . 3112636 .
2. Pawłowski L, Kwiatek H, Górka Z . Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors? . Journal of Neural Transmission . 1981 . 52 . 1–2 . 61–72 . 10.1007/BF01253098 . 7288439 . 41042435 .
3. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 270–.