Chromosome 9 Explained

Length Bp:150,617,247 bp
(CHM13)
Genes:739 (CCDS)
Type:Autosome
Centromere Position:Submetacentric[1]
(43.0 Mbp[2])
Chr:9
Ensembl Id:9
Entrez Id:9
Ncbi Id:9
Ucsc Id:9
Refseq Id:NC_000009
Genbank Id:CM000671

Chromosome 9 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome, as they normally do with all chromosomes. Chromosome 9 spans about 150 million base pairs of nucleic acids (the building blocks of DNA) and represents between 4.0 and 4.5% of the total DNA in cells.

Genes

Number of genes

These are some of the gene count estimates of human chromosome 9. Because researchers use different approaches to genome annotation, their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.[3]

Estimated byProtein-coding genesNoncoding RNA genesPseudogenesSourceRelease date
739 — —[4] 2016-09-08
HGNC749 246 590[5] 2017-05-12
775 788 663[6] 2017-03-29
812 — —[7] 2018-02-28
822 830 738[8] [9] [10] 2017-05-19

Gene list

The following is a partial list of genes on human chromosome 9. For a complete list, see the link in the infobox on the right.

Diseases and disorders

The following diseases are some of those related to genes on chromosome 9:

Cytogenetic band

G-bands of human chromosome 9 in resolution 850 bphs[11] ! Chr. ! Arm[12] ! Band[13] ! ISCN
start[14] ! ISCN
stop! Basepair
start ! Basepair
stop ! Stain[15] ! Density
9 p 24.3 0 127 gneg
9 p 24.2 127 268 gpos 25
9 p 24.1 268 451 gneg
9 p 23 451 677 gpos 75
9 p 22.3 677 846 gneg
9 p 22.2 846 987 gpos 25
9 p 22.1 987 1085 gneg
9 p 21.3 1085 1297 gpos 100
9 p 21.2 1297 1395 gneg
9 p 21.1 1395 1621 gpos 100
9 p 13.3 1621 1917 gneg
9 p 13.2 1917 2030 gpos 25
9 p 13.1 2030 2171 gneg
9 p 12 2171 2312 gpos 50
9 p 11.2 2312 2523 gneg
9 p 11.1 2523 2650 acen
9 q 11 2650 2876 acen
9 q 12 2876 3468 gvar
9 q 13 3468 3609 gneg
9 q 21.11 3609 3792 gpos 25
9 q 21.12 3792 3876 gneg
9 q 21.13 3876 4060 gpos 50
9 q 21.2 4060 4229 gneg
9 q 21.31 4229 4440 gpos 50
9 q 21.32 4440 4638 gneg
9 q 21.33 4638 4835 gpos 50
9 q 22.1 4835 5074 gneg
9 q 22.2 5074 5173 gpos 25
9 q 22.31 5173 5314 gneg
9 q 22.32 5314 5455 gpos 25
9 q 22.33 5455 5638 gneg
9 q 31.1 5638 5892 gpos 100
9 q 31.2 5892 6005 gneg
9 q 31.3 6005 6146 gpos 25
9 q 32 6146 6456 gneg
9 q 33.1 6456 6681 gpos 75
9 q 33.2 6681 6822 gneg
9 q 33.3 6822 6949 gpos 25
9 q 34.11 6949 7217 gneg
9 q 34.12 7217 7302 gpos 25
9 q 34.13 7302 7443 gneg
9 q 34.2 7443 7555 gpos 25
9 q 34.3 7555 7950 gneg

References

External links

Notes and References

  1. Book: Tom Strachan. Andrew Read. Human Molecular Genetics. 2 April 2010. Garland Science. 978-1-136-84407-2. 45.
  2. Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
  3. Pertea M, Salzberg SL. Between a chicken and a grape: estimating the number of human genes. . Genome Biol . 2010 . 11 . 5 . 206 . 20441615 . 10.1186/gb-2010-11-5-206 . 2898077 . free .
  4. Web site: Search results - 1[CHR] AND "Homo sapiens"[Organism] AND ("has ccds"[Properties] AND alive[prop]) - Gene . NCBI . CCDS Release 20 for Homo sapiens . 2016-09-08 . 2017-05-28.
  5. Web site: Statistics & Downloads for chromosome 9 . HUGO Gene Nomenclature Committee . 2017-05-12 . 2017-05-19 . 2021-03-20 . https://web.archive.org/web/20210320210745/https://www.genenames.org/download/statistics-and-files/?c=9 . dead .
  6. Web site: Chromosome 9: Chromosome summary - Homo sapiens . Ensembl Release 88 . 2017-03-29 . 2017-05-19.
  7. Web site: Human chromosome 9: entries, gene names and cross-references to MIM . UniProt . 2018-02-28 . 2018-03-16.
  8. Web site: Search results - 9[CHR] AND "Homo sapiens"[Organism] AND ("genetype protein coding"[Properties] AND alive[prop]) - Gene . NCBI . 2017-05-19 . 2017-05-20.
  9. Web site: Search results - 9[CHR] AND "Homo sapiens"[Organism] AND (("genetype miscrna"[Properties] OR "genetype ncrna"[Properties] OR "genetype rrna"[Properties] OR "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) NOT "genetype protein coding"[Properties] AND alive[prop]) - Gene . NCBI . 2017-05-19 . 2017-05-20.
  10. Web site: Search results - 9[CHR] AND "Homo sapiens"[Organism] AND ("genetype pseudo"[Properties] AND alive[prop]) - Gene . NCBI . 2017-05-19 . 2017-05-20.
  11. Genome Decoration Page, NCBI. Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3). Last update 2014-06-03. Retrieved 2017-04-26.
  12. "p": Short arm; "q": Long arm.
  13. For cytogenetic banding nomenclature, see article locus.
  14. These values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013). Arbitrary unit.
  15. gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region which is negatively stained by G banding, generally CG-rich and gene rich; acen Centromere. var: Variable region; stalk: Stalk.

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