Chondromyxoid fibroma explained
Chondromyxoid fibroma is a rare type of cartilaginous tumor.[1] Rarely occur in the skull or skull base.[2]
Most cases are characterised by GRM1 gene fusion or promoter swapping.[3] It can be associated with a translocation at t(1;5)(p13;p13).[4]
Notes and References
- Hakan T, Vardar Aker F . Chondromyxoid fibroma of frontal bone: a case report and review of the literature . Turk Neurosurg . 18 . 3 . 249–53 . July 2008 . 18814113 .
- Thompson AL, Bharatha A, Aviv RI, Nedzelski J, Chen J, Bilbao JM, Wong J, Saad R, Symons SP . July 2009 . Chondromyoid fibroma of the mastoid facial nerve canal mimicking a facial nerve schwannoma . Laryngoscope . 119 . 7. 1380–1383 . 10.1002/lary.20486. 19507235 . 34800452 .
- Nord KH, Lilljebjörn H, Vezzi F . GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma . Nat Genet . 46 . 5 . 474–7 . 2014 . 24658000 . 10.1038/ng.2927 . 20990305 . etal. 1887/104849 . free .
- Armah HB, McGough RL, Goodman MA . Chondromyxoid fibroma of rib with a novel chromosomal translocation: a report of four additional cases at unusual sites . Diagn Pathol . 2 . 44 . 2007 . 18036245 . 2203974 . 10.1186/1746-1596-2-44 . etal . free .
