Chlorophyllide a reductase explained

Chlorophyllide a reductase
Ec Number:	1.3.7.15

Chlorophyllide a reductase, also known as COR, is an enzyme with systematic name bacteriochlorophyllide-a:ferredoxin 7,8-oxidoreductase.^{[1] [2]} It catalyses the following chemical reaction

chlorophyllide a + 2 reduced ferredoxin + ATP + H₂O + 2 H⁺

\rightleftharpoons 3-deacetyl 3-vinylbacteriochlorophyllide a + 2 oxidized ferredoxin + ADP + phosphateThis reduction (with trans stereochemistry) of the pyrrole ring B, gives the characteristic 18-electron aromatic system that distinguishes bacteriochlorophylls from chlorophylls, which retain the chlorin system of Chlorophyllide a.This enzyme is present in purple bacteria such as Rhodobacter capsulatus and Rhodobacter sphaeroides, and Pseudomonadota. It is a component of the biosynthetic pathway to bacteriochlorophylls.^{[3] [4] [5]}

See also

• Biosynthesis of bacteriochlorophylls

Notes and References

1. 10.1074/jbc.M113.546739. Chlorophyllide a Oxidoreductase Works as One of the Divinyl Reductases Specifically Involved in Bacteriochlorophyll a Biosynthesis. 2014. Harada. Jiro. Mizoguchi. Tadashi. Tsukatani. Yusuke. Yokono. Makio. Tanaka. Ayumi. Tamiaki. Hitoshi. Journal of Biological Chemistry. 289. 18. 12716–12726. 24637023. 4007461. free.
2. 10.1038/srep09741. Rhodobacter sphaeroides mutants overexpressing chlorophyllide a oxidoreductase of Blastochloris viridis elucidate functions of enzymes in late bacteriochlorophyll biosynthetic pathways. 2015. Tsukatani. Yusuke. Harada. Jiro. Nomata. Jiro. Yamamoto. Haruki. Fujita. Yuichi. Mizoguchi. Tadashi. Tamiaki. Hitoshi. Scientific Reports. 5. 9741. 25978726. 4432870. 2015NatSR...5E9741T.
3. Web site: Pathway: bacteriochlorophyll a biosynthesis . R. Caspi . MetaCyc Metabolic Pathway Database . 2015-12-08 . 2020-06-04 .
4. Willows RD . Biosynthesis of chlorophylls from protoporphyrin IX . Natural Product Reports . 20 . 3 . 327–41 . June 2003 . 12828371 . 10.1039/B110549N .
5. Bollivar DW . Recent advances in chlorophyll biosynthesis . Photosynthesis Research . 90 . 2 . 173–94 . November 2006 . 17370354 . 10.1007/s11120-006-9076-6 . 23808539 .