Chitobiosyldiphosphodolichol beta-mannosyltransferase explained

chitobiosyldiphosphodolichol beta-mannosyltransferase
Ec Number:2.4.1.142
Cas Number:83380-85-2
Go Code:0004578

In enzymology, a chitobiosyldiphosphodolichol beta-mannosyltransferase is an enzyme that catalyzes the chemical reaction

GDP-mannose + chitobiosyldiphosphodolichol

\rightleftharpoons

GDP + beta-1,4-D-mannosylchitobiosyldiphosphodolichol

Thus, the two substrates of this enzyme are GDP-mannose and chitobiosyldiphosphodolichol, whereas its two products are GDP and beta-1,4-D-mannosylchitobiosyldiphosphodolichol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase. Other names in common use include guanosine diphosphomannose-dolichol diphosphochitobiose, mannosyltransferase, and GDP-mannose-dolichol diphosphochitobiose mannosyltransferase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.

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