Cheilanthifoline Explained

(S)-Cheilanthifoline is a benzylisoquinoline alkaloid (BIA) which has been isolated from Corydalis dubia[1] and Argemone mexicana. (S)-Cheilanthifoline is metabolically derived from (S)-reticuline, a pivotal intermediate in the biosynthesis of numerous BIAs. (S)-Cheilanthifoline is the immediate precursor of the BIA (S)-stylopine ((S)-stylopine synthase/CYP719A20), which is the precursor for the alkaloids protopine and sanguinarine.[2]

Notes and References

  1. 22796506. 2012. Wangchuk. P. Keller. PA. Pyne. SG. Willis. AC. Kamchonwongpaisan. S. Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia . 143. 1. 310–3. 10.1016/j.jep.2012.06.037. Journal of Ethnopharmacology.
  2. Hagel . Jillian . Morris. Jeremy S. Lee. Eun-Jeong. Desgagne-Penix. Isabel. Bross. Crystal D. Chang. Limei. Chen. Xue. Farrow. Scott C. Zhang. Te. 2015. Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants. BMC Plant Biology. 15. 227. 10.1186/s12870-015-0596-0. 26384972. 4575454 . free .

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