Chalcone 4'-O-glucosyltransferase explained

Chalcone 4'-O-glucosyltransferase
Ec Number:	2.4.1.286

Chalcone 4'-O-glucosyltransferase (4'CGT) is an enzyme with systematic name UDP-alpha-D-glucose:2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucosyltransferase.^[1] This enzyme catalyses the following chemical reaction

(1) UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone

\rightleftharpoons UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside

(2) UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone

\rightleftharpoons UDP + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside

This enzyme is isolated from the plant Antirrhinum majus (snapdragon).

Notes and References

1. Ono E, Fukuchi-Mizutani M, Nakamura N, Fukui Y, Yonekura-Sakakibara K, Yamaguchi M, Nakayama T, Tanaka T, Kusumi T, Tanaka Y . Yellow flowers generated by expression of the aurone biosynthetic pathway . Proceedings of the National Academy of Sciences of the United States of America . 103 . 29 . 11075–80 . July 2006 . 16832053 . 1544175 . 10.1073/pnas.0604246103 . 2006PNAS..10311075O . free .