Ceramide glucosyltransferase explained
| Ceramide glucosyltransferase |
| Ec Number: | 2.4.1.80 |
| Cas Number: | 37237-44-8 |
Ceramide glucosyltransferase (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucocerebroside.[1]
It is classified under .
It is inhibited by miglustat and eliglustat, both drugs developed for the treatment of Gaucher disease.
See also
Notes and References
- Ichikawa S, Sakiyama H, Suzuki G, Hidari KI, Hirabayashi Y . Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis . Proceedings of the National Academy of Sciences of the United States of America . 93 . 10 . 4638–43 . May 1996 . 8643456 . 39331 . 10.1073/pnas.93.10.4638 . free .
