Ceramide cholinephosphotransferase explained

ceramide cholinephosphotransferase
Ec Number:2.7.8.3
Cas Number:9026-14-6
Go Code:0047493

In enzymology, a ceramide cholinephosphotransferase is an enzyme that catalyzes the chemical reaction

CDP-choline + N-acylsphingosine

\rightleftharpoons

CMP + sphingomyelin

Thus, the two substrates of this enzyme are CDP-choline and N-acylsphingosine, whereas its two products are CMP and sphingomyelin.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:N-acylsphingosine cholinephosphotransferase. This enzyme is also called phosphorylcholine-ceramide transferase. This enzyme participates in sphingolipid metabolism.

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