Catechol 2,3-dioxygenase explained

Catechol 2,3-dioxygenase
Ec Number:	1.13.11.2
Cas Number:	9029-46-3
Width:	270

Catechol 2,3-dioxygenase (2,3-pyrocatechase, catechol 2,3-oxygenase, catechol oxygenase, metapyrocatechase, pyrocatechol 2,3-dioxygenase) is an enzyme with systematic name catechol:oxygen 2,3-oxidoreductase (decyclizing).^{[1] [2] [3] [4] [5]} This enzyme catalyses the following chemical reaction

catechol + O₂

\rightleftharpoons 2-hydroxymuconate semialdehyde

This enzyme contains Fe(II).

Notes and References

1. Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM . Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid . The Biochemical Journal . 300 (Pt 2) . 2 . 429–36 . June 1994 . 8002948 . 1138180 . 10.1042/bj3000429 .
2. Junker F, Leisinger T, Cook AM . 3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1 . Microbiology . 140 (Pt 7) . 7 . 1713–22 . July 1994 . 8075807 . 10.1099/13500872-140-7-1713 . free .
3. Book: Direct oxygenation by O₂, oxygenases . The Enzymes . Hayaishi O, Lardy H, Myrbäck K . 1963 . 8 . 353–371 . Boyer PD . 2nd . Academic Press . New York .
4. Kojima Y, Itada N, Hayaishi O . Metapyrocatachase: a new catechol-cleaving enzyme . The Journal of Biological Chemistry . 236 . 2223–8 . August 1961 . 13757654 .
5. Nozaki M, Kagamiyama H, Hayaishi O . Metapyrocatechase. I. Purification, Crystallization and Some Properties . Biochemische Zeitschrift . 338 . 582–90 . 1963 . 14087325 .