Carnitine 3-dehydrogenase explained

carnitine 3-dehydrogenase
Ec Number:	1.1.1.108
Cas Number:	9045-45-8
Go Code:	0047728

In enzymology, a carnitine 3-dehydrogenase is an enzyme that catalyzes the chemical reaction

carnitine + NAD⁺

\rightleftharpoons 3-dehydrocarnitine + NADH + H⁺

Thus, the two substrates of this enzyme are carnitine and NAD⁺, whereas its 3 products are 3-dehydrocarnitine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is carnitine:NAD⁺ 3-oxidoreductase.

References

• Aurich H, Kleber HP, Sorger H, Tauchert H . 1968 . Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa . German . Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa . Eur. J. Biochem. . 6 . 196 - 201 . 4302217 . 10.1111/j.1432-1033.1968.tb00437.x . 2 .
• Schopp W, Sorger H, Kleber HP, Aurich H . 1969 . Kinetische Untersuchungen zum Reaktionsmechanismus der Carnitindehydrogenase aus Pseudomonas aeruginosa . German . Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa . Eur. J. Biochem. . 10 . 56 - 60 . 4310279 . 1 . 10.1111/j.1432-1033.1969.tb00654.x . free .