Butirosin Explained

Inn:Butirosin
Cas Number:12772-35-9
Class:Aminoglycoside antibiotic
Pubchem:72393
Chemspiderid:65326
Chebi:65109
Kegg:C01559
Unii:8S52KR0L58
Smiles:C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@@H](CCN)O)O)O[C@@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N
Stdinchi:1S/C21H41N5O12/c22-2-1-8(28)19(34)26-7-3-6(24)17(37-20-11(25)15(32)13(30)9(4-23)35-20)18(12(7)29)38-21-16(33)14(31)10(5-27)36-21/h6-18,20-21,27-33H,1-5,22-25H2,(H,26,34)/t6-,7+,8+,9+,10+,11+,12-,13+,14+,15+,16+,17+,18+,20+,21+/m0/s1
Stdinchikey:XEQLFNPSYWZPOW-NUOYRARPSA-N
Synonyms:Ambutyrosin; Butyrosin

Butirosin is an aminoglycoside antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.[1] It is a mixture with butirosin A (80-85%) and butirosin B being the major components.[2]

Notes and References

  1. Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO . Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice . Antimicrobial Agents and Chemotherapy . 2 . 2 . 89–94 . August 1972 . 4670492 . 444273 . 10.1128/aac.2.2.89 .
  2. Book: The Dictionary of Drugs . Elks J . Springer . 2014 . 198.