Buclizine Explained

Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.[1]

In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines.[2]

Notes and References

  1. Mostafa GA, Al-Badr AA . Buclizine . Profiles Drug Subst Excip Relat Methodol . 36 . 1–33 . 2011 . 22469258 . 10.1016/B978-0-12-387667-6.00001-4 . Profiles of Drug Substances, Excipients and Related Methodology . 9780123876676 .
  2. Behrendt WA, Cserepes J . Acute toxicity and analgesic action of a combination of buclizine, codeine and paracetamol ('Migraleve') in tablet and suppository form in rats . Pharmatherapeutica . 4 . 5 . 322–31 . 1985 . 4070325 .

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