Brutieridin Explained

Brutieridin is a flavanone glycoside. Brutieridin was discovered in bergamot orange juice and exhibits statin-like properties in preclinical research,^{[1] [2] [3]} as well as an anticholesterolaemic effect.^{[4] [5]}

See also

• Melitidin

Bibliography

• Di Donna. Leonardo. Taverna. Domenico. Mazzotti. Fabio. Benabdelkamel. Hicham. Attya. Mohamed. Napoli. Anna. Sindona. Giovanni. Comprehensive assay of flavanones in citrus juices and beverages by UHPLC–ESI-MS/MS and derivatization chemistry. Food Chemistry. 141. 3. 2013. 2328–2333. 0308-8146. 10.1016/j.foodchem.2013.05.034. 23870965.
• Mencherini. Teresa. Campone. Luca. Piccinelli. Anna Lisa. García Mesa. Milagros. Sánchez. Dulce María. Aquino. Rita Patrizia. Rastrelli. Luca. HPLC-PDA-MS and NMR Characterization of a Hydroalcoholic Extract of Citrus aurantium L. var.amara Peel with Antiedematogenic Activity. Journal of Agricultural and Food Chemistry. 61. 8. 2013. 1686–1693. 0021-8561. 10.1021/jf302815t. 22957519.
• Barreca. Davide. Bellocco. Ersilia. Caristi. Corrado. Leuzzi. Ugo. Gattuso. Giuseppe. Distribution of C- and O-glycosyl flavonoids, (3-hydroxy-3-methylglutaryl)glycosyl flavanones and furocoumarins in Citrus aurantium L. juice. Food Chemistry. 124. 2. 2011. 576–582. 0308-8146. 10.1016/j.foodchem.2010.06.076.
• Di Donna. Leonardo. Taverna. Domenico. Mazzotti. Fabio. Benabdelkamel. Hicham. Attya. Mohamed. Napoli. Anna. Sindona. Giovanni. Comprehensive assay of flavanones in citrus juices and beverages by UHPLC–ESI-MS/MS and derivatization chemistry. Food Chemistry. 141. 3. 2013. 2328–2333. 0308-8146. 10.1016/j.foodchem.2013.05.034. 23870965.

Notes and References

1. Natalizia Miceli . M. R. Mondello . M. T. Monforte . V. Sdrafkakis . P. Dugo . M. L. Crupi . M. F. Taviano . R. De Pasquale . A. Trovato . amp . Hypolipidemic Effects of Citrus bergamia Risso et Poiteau Juice in Rats Fed a Hypercholesterolemic Diet. 2007. J. Agric. Food Chem.. 55. 27. 10671–10677. 10.1021/jf071772i. 18038978 .
2. Monica Leopoldini . N. Malaj . M. Toscano . G. Sindona . N. Russo . amp . On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme. 2010. J. Agric. Food Chem.. 58. 19. 10768–10773. 10.1021/jf102576j. 20843083 .
3. Vincenzo Mollace . I. Sacco . E. Janda . C. Malara . D. Ventrice . C. Colica . V. Visalli . S. Muscoli . S. Ragusa . C. Muscoli . D. Rotirotia . F. Romeo . Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies. 2011. Fitoterapia. 82. 3. 309–316. 10.1016/j.fitote.2010.10.014 . 21056640. PDF
4. Di Donna. Leonardo . De Luca, Giuseppina . Mazzotti, Fabio . Napoli, Anna . Salerno, Raffaele . Taverna, Domenico . Sindona, Giovanni . Statin-like Principles of Bergamot Fruit: Isolation of 3-Hydroxymethylglutaryl Flavonoid Glycosides. Journal of Natural Products. 2009. 72. 7. 1352–1354. 10.1021/np900096w. 19572741.
5. Di Donna. Leonardo. Gallucci. Giselda. Malaj. Naim. Romano. Elvira. Tagarelli. Antonio. Sindona. Giovanni. Recycling of industrial essential oil waste: Brutieridin and Melitidin, two anticholesterolaemic active principles from bergamot albedo. Food Chemistry. 125. 2. 2011. 438–441. 0308-8146. 10.1016/j.foodchem.2010.09.025.