Bromethenmadinone acetate explained

Bromethenmadinone acetate (BMMA, also known as bromsuperlutin) is a progestin medication which was developed in Czechoslovakia and was described in 1970 but was never marketed.^{[1] [2] [3] [4] [5] [6] [7] [8] [9]} Analogues of BMMA include chlormethenmadinone acetate, melengestrol acetate, and methenmadinone acetate.

See also

• List of progestogen esters § Esters of 17α-hydroxyprogesterone derivatives
• 16-Methylene-17α-hydroxyprogesterone acetate

Notes and References

1. Stĕrba R . [Towards a more physiological hormonal contraception] ]. de . Zentralbl Gynakol . 92 . 10 . 303–12 . March 1970 . 4096927 . 2018-09-17 . https://web.archive.org/web/20180916202323/https://www.popline.org/node/470458 . 2018-09-16 . dead .
2. Book: Štěrba. R.. Current Problems in Fertility. On the Way to a More Physiological Hormonal Contraception. 1971. 154–158. 10.1007/978-1-4615-8651-7_28. https://www.popline.org/node/480951. 978-1-4615-8653-1. 2018-09-17. 2018-09-16. https://web.archive.org/web/20180916202608/https://www.popline.org/node/480951. dead.
3. Cekan Z, Horesovský O . Elimination and metabolism of 6-chloro-17-alpha-hydroxy-16-methylene-4,6-pregnadiene-3,20-dione acetate and its analogues in rats . Acta Endocrinol. . 66 . 2 . 303–16 . February 1971 . 5107826 . 10.1530/acta.0.0660303 .
4. Shapiro EL, Weber L, Harris H, Miskowicz C, Neri R, Herzog HL . Synthesis and biological activity of 17-esters of 6-dehydro-16-methylene-17 -hydroxyprogesterones . J. Med. Chem. . 15 . 7 . 716–20 . July 1972 . 5043870 . 10.1021/jm00277a006 .
5. Míčková. R.. Steroid derivatives. LXXV. The preparation of polyhalogenated derivatives of progestational hormones and the determination of their conformation by circular dichroism spectra. Collection of Czechoslovak Chemical Communications. 38. 8. 1973. 2492–2503. 0010-0765. 10.1135/cccc19732492.
6. Wolff ME . A quantitative reexamination of structure-activity relationships in the delta6-6-substituted progesterone series . J. Med. Chem. . 17 . 8 . 898–900 . August 1974 . 4845383 . 10.1021/jm00254a025 .
7. Topliss JG, Shapiro EL . Quantitative structure-activity relationships in the delta6-6-substituted progesterone series. A reappraisal . J. Med. Chem. . 18 . 6 . 621–3 . June 1975 . 1151979 . 10.1021/jm00240a020 .
8. Wolff ME, Hansch C, Giannini DD, Kollman PA, Duax WL, Baxter J . Correlation of glucocorticoid and progestational activity with steric, electronic and hydrophobic parameters . J. Steroid Biochem. . 6 . 3–4 . 211–4 . 1975 . 171485 . 10.1016/0022-4731(75)90134-X .
9. Coburn RA, Solo AJ . Quantitative structure-activity relationships among steroids. Investigations of the use of steric parameters . J. Med. Chem. . 19 . 6 . 748–54 . June 1976 . 950640 . 10.1021/jm00228a002 .