Bisphosphoglycerate phosphatase explained

bisphosphoglycerate phosphatase
Ec Number:3.1.3.13
Cas Number:9033-04-9
Go Code:0004083
Width:270

In enzymology, a bisphosphoglycerate phosphatase is an enzyme that catalyzes the chemical reaction

2,3-bisphospho-D-glycerate + H2O

\rightleftharpoons

3-phospho-D-glycerate + phosphate

Thus, the two substrates of this enzyme are 2,3-bisphospho-D-glycerate and H2O, whereas its two products are 3-phospho-D-glycerate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 2,3-bisphospho-D-glycerate 2-phosphohydrolase. Other names in common use include 2,3-diphosphoglycerate phosphatase, diphosphoglycerate phosphatase, 2,3-diphosphoglyceric acid phosphatase, 2,3-bisphosphoglycerate phosphatase, and glycerate-2,3-diphosphate phosphatase. This enzyme participates in glycolysis/gluconeogenesis.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes,,,,,, and .

References