Bis(pinacolato)diboron explained

Bis(pinacolato)diboron is a covalent compound containing two boron atoms and two pinacolato ligands. It has the formula [(CH<sub>3</sub>)<sub>4</sub>C<sub>2</sub>O<sub>2</sub>B]2; the pinacol groups are sometimes abbreviated as "pin", so the structure is sometimes represented as B2pin2. It is a colourless solid that is soluble in organic solvents. It is a commercially available reagent for making pinacol boronic esters for organic synthesis. Unlike some other diboron compounds, B2pin2 is not moisture-sensitive and can be handled in air.

Preparation and structure

This compound may be prepared by treating tetrakis(dimethylamino)diboron with pinacol in acidic conditions. The B-B bond length is 1.711(6) Å.

Dehydrogenation of pinacolborane provides an alternative route:[1]

2(CH3)4C2O2BH → (CH3)4C2O2B-BO2C2(CH3)4 + H2

Reactions

thumb|left|Pinacolborane is a closely related reagent.|110pxThe B-B bond adds across alkenes and alkynes to give the 1,2-diborylated alkanes and alkenes. Using various organorhodium or organoiridium catalysts, it can also be installed onto saturated hydrocarbons:[2]

CH3(CH2)6CH3 + [pinB]2 → pinBH + CH3(CH2)7BpinThese reactions proceed via boryl complexes.Bis(pinacolato)diboron can also be used as reducing agent for example in transition metal catalyzed hydrogenations of alkenes and alkynes. [3]

Notes and References

  1. 10.1021/acs.chemrev.6b00193. Diboron(4) Compounds: From Structural Curiosity to Synthetic Workhorse. 2016. Neeve. Emily C.. Geier. Stephen J.. Mkhalid. Ibraheem A. I.. Westcott. Stephen A.. Marder. Todd B.. Chemical Reviews. 116. 16. 9091–9161. 27434758. free. 1807/78811. free.
  2. Xinyu Liu "Bis(pinacolato)diboron"Synlett 2003, pp 2442–2443.
  3. Web site: Bis(pinacolato)diboron, B2pin2.