| Biotin—CoA ligase | |
| Ec Number: | 6.2.1.11 |
| Cas Number: | 37318-60-8 |
| Go Code: | 0047707 |
In enzymology, a biotin—CoA ligase is an enzyme that catalyzes the chemical reaction
ATP + biotin + CoA
\rightleftharpoons
The 3 substrates of this enzyme are ATP, biotin, and CoA, whereas its 3 products are AMP, diphosphate, and biotinyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is biotin:CoA ligase (AMP-forming). Other names in common use include biotinyl-CoA synthetase, biotin CoA synthetase, and biotinyl coenzyme A synthetase. This enzyme participates in biotin metabolism.