Bilirubin diglucuronide explained

Bilirubin di-glucuronide is a conjugated form of bilirubin formed in bilirubin metabolism.[1] The hydrophilic character of bilirubin diglucuronide enables it to be water-soluble. It is pumped across the hepatic canalicular membrane into the bile by the transporter MRP2.[2]

See also

Notes and References

  1. 6796486. 1981. Chowdhury. J. R.. Bilirubin mono- and diglucuronide formation by human liver in vitro: Assay by high-pressure liquid chromatography. Hepatology. 1. 6. 622–7. Chowdhury. N. R.. Wu. G.. Shouval. R.. Arias. I. M.. 10.1002/hep.1840010610.
  2. Lengyel . G. . Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes. Hepatology Research . 38 . 3 . 300–309 . Wiley. 2007-08-29 . 10.1111/j.1872-034X.2007.00255.x. 17760873 . etal.

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