Β-Naphthoflavone Explained

β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and as such is an inducer of such detoxification enzymes as cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs).^[1] β-Naphthoflavone is a putative chemopreventive agent.^[2]

See also

• α-Naphthoflavone

References

1. Chlouchi A, Girard C, Bonet A, Viollon-Abadie C, Heyd B, Mantion G, Martin H, Richert L . Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture . Planta Med. 73 . 8 . 742–7. 2007 . 17599282 . 10.1055/s-2007-981548. 260281088 .
2. Izzotti A, Bagnasco M, Cartiglia C, Longobardi M, Camoirano A, Tampa E, Lubet RA, De Flora S . Modulation of multigene expression and proteome profiles by chemopreventive agents . Mutat Res . 591. 1–2 . 212–23. 2005 . 16083920 . 10.1016/j.mrfmmm.2005.03.032.