Beta-D-galactosyl-(1-4)-L-rhamnose phosphorylase explained

Beta-D-galactosyl-(1->4)-L-rhamnose phosphorylase
Ec Number:2.4.1.247
Cas Number:1236189-79-9

Beta-D-galactosyl-(1->4)-L-rhamnose phosphorylase (D-galactosyl-beta1->4-L-rhamnose phosphorylase, GalRhaP) is an enzyme with systematic name beta-D-galactosyl-(1->4)-L-rhamnose:phosphate 1-alpha-D-galactosyltransferase.[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons

L-rhamnose + alpha-D-galactose 1-phosphate

The enzyme from Clostridium phytofermentans is also active towards beta-D-galactosyl derivatives of L-mannose, L-lyxose, D-glucose, 2-deoxy-D-glucose, and D-galactose.

Notes and References

  1. Nakajima M, Nishimoto M, Kitaoka M . Characterization of three beta-galactoside phosphorylases from Clostridium phytofermentans: discovery of d-galactosyl-beta1->4-l-rhamnose phosphorylase . The Journal of Biological Chemistry . 284 . 29 . 19220–7 . July 2009 . 19491100 . 2740546 . 10.1074/jbc.m109.007666 . free .