Bazedoxifene/conjugated estrogens explained

Type:combo
Component1:Bazedoxifene
Class1:Selective estrogen receptor modulator
Component2:Conjugated estrogens
Class2:Estrogen
Tradename:Duavee, Duavive
Dailymedid:Duavee
Pregnancy Au:D
Pregnancy Au Comment:[1]
Routes Of Administration:By mouth
Atc Prefix:G03
Atc Suffix:CC07
Legal Us:Rx-only
Legal Us Comment:[2]
Legal Eu:Rx-only
Legal Status:Rx-only
Cas Number:1422348-02-4
Chemspiderid:None
Kegg:D10579

Bazedoxifene/conjugated estrogens, sold under the brand name Duavee in the US and Duavive in the EU, is a fixed-dose combination medication for the treatment of menopause symptoms and postmenopausal osteoporosis.[3] [4] [5] It contains the selective estrogen receptor modulator bazedoxifene and conjugated estrogens. It is taken by mouth.

The combination was approved for medical use in the United States in October 2013,[6] and in the European Union in December 2014.[7]

See also

External links

Notes and References

  1. Web site: Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy . Drugs.com . 16 February 2019 . 23 June 2020.
  2. Web site: Duavee- conjugated estrogens/bazedoxifene tablet, film coated . DailyMed . 16 July 2021 . 21 February 2022.
  3. Web site: Duavee. Generic Name: conjugated estrogens and bazedoxifene tablets . rxlist.com.
  4. Palacios S, Mejía Ríos A . Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women . Drugs of Today . 51 . 2 . 107–16 . February 2015 . 25756066 . 10.1358/dot.2015.51.2.2281023 .
  5. Lello S, Capozzi A, Scambia G . The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause . International Journal of Endocrinology . 2017 . 5064725 . 2017 . 29358948 . 5735652 . 10.1155/2017/5064725 . free .
  6. Web site: Drug Approval Package: Duavee (conjugated estrogens and bazedoxifene) NDA #022247 . U.S. Food and Drug Administration (FDA) . 7 October 2013 . 23 June 2020.
  7. Web site: Duavive EPAR . 10 June 2020. European Medicines Agency (EMA). 17 September 2018 .

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