| Conflict: | Battle of Huarina |
| Partof: | the Spanish conquest of Peru |
| Date: | October 20, 1547 |
| Place: | Huarina, present-day Bolivia |
| Result: | Decisive victory for Nueva Castilla |
| Combatant1: | Viceroyalty of Peru |
| Combatant2: | Nueva Castilla |
| Commander1: | Diego Centeno |
| Commander2: | Francisco de Carvajal, Gonzalo Pizarro |
| Strength1: | 750 infantry, 250 cavalry[1] |
| Strength2: | 480 |
| Casualties1: | 350 dead, ~350 wounded[2] |
| Casualties2: | 100 dead |
After sending away royal appointed governor of the Viceroyalty of Peru, Blasco Núñez Vela and later defeating and killing him in the battle of Añaquito, Gonzalo Pizarro assembled an army of 1,200 men to press claims for the rule over Peru, once belonging to him and his brothers. The new viceroy, Pedro de la Gasca, landed in Peru in 1547, and a contingent of his troops, led by Diego Centeno, was severely defeated at Huarina by Francisco de Carvajal (dubbed the Demon of the Andes, for his treatment of native Peruvians in his quest for glory and power.)
Centeno, however, remained successful in retreating in order and later united with the main force under de la Gasca. Ultimately, the viceroy won the cause of most of Gonzalo Pizarro's officers and men, and on April 9, 1548, the pizarrists were finally overthrown in the battle of Jaquijahuana.