Bacillolysin Explained

Bacillolysin
Ec Number:3.4.24.28
Cas Number:9080-56-2

Bacillolysin (Bacillus metalloendopeptidase, Bacillus subtilis neutral proteinase, anilozyme P 10, Bacillus metalloproteinase, Bacillus neutral proteinase, megateriopeptidase) is an enzyme.[1] [2] [3] [4] [5] [6] [7] [8] [9] [10] This enzyme catalyses the following chemical reaction

Similar, but not identical, to that of thermolysin

This enzyme is present in many Bacillus species, including B. subtilis, B. amyloliquefaciens, B. megaterium, B. mesentericus, B. cereus and B. stearothermophilus.

Notes and References

  1. Morihara K, Tsuzuki H, Oka T . Comparison of the specificities of various neutral proteinases from microorganisms . Archives of Biochemistry and Biophysics . 123 . 3 . 572–88 . March 1968 . 4967801 . 10.1016/0003-9861(68)90179-3 .
  2. Millet J, Acher R . [Specificity of megateriopeptidase: an amino-endopeptidase with hydrophobic characteristics] . European Journal of Biochemistry . 9 . 4 . 456–62 . July 1969 . 4980359 . 10.1111/j.1432-1033.1969.tb00631.x . free .
  3. Feder J, Keay L, Garrett LR, Cirulis N, Moseley MH, Wildi BS . Bacillus cereus neutral protease . Biochimica et Biophysica Acta (BBA) - Protein Structure . 251 . 1 . 74–8 . October 1971 . 5002444 . 10.1016/0005-2795(71)90061-4 .
  4. Holmquist B, Vallee BL . Esterase activity of zinc neutral proteases . Biochemistry . 15 . 1 . 101–7 . January 1976 . 2276 . 10.1021/bi00646a016 .
  5. Vasantha N, Thompson LD, Rhodes C, Banner C, Nagle J, Filpula D . Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein . Journal of Bacteriology . 159 . 3 . 811–9 . September 1984 . 10.1128/JB.159.3.811-819.1984 . 6090391 . 215730 .
  6. Yang MY, Ferrari E, Henner DJ . Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation . Journal of Bacteriology . 160 . 1 . 15–21 . October 1984 . 10.1128/JB.160.1.15-21.1984 . 6090407 . 214674 .
  7. Takagi M, Imanaka T, Aiba S . Nucleotide sequence and promoter region for the neutral protease gene from Bacillus stearothermophilus . Journal of Bacteriology . 163 . 3 . 824–31 . September 1985 . 10.1128/JB.163.3.824-831.1985 . 2993245 . 219205 .
  8. Sidler W, Niederer E, Suter F, Zuber H . The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase . Biological Chemistry Hoppe-Seyler . 367 . 7 . 643–57 . July 1986 . 3092843 . 10.1515/bchm3.1986.367.2.643 .
  9. Pauptit RA, Karlsson R, Picot D, Jenkins JA, Niklaus-Reimer AS, Jansonius JN . Crystal structure of neutral protease from Bacillus cereus refined at 3.0 A resolution and comparison with the homologous but more thermostable enzyme thermolysin . Journal of Molecular Biology . 199 . 3 . 525–37 . February 1988 . 3127592 . 10.1016/0022-2836(88)90623-7 .
  10. Stoeva S, Kleinschmidt T, Mesrob B, Braunitzer G . Primary structure of a zinc protease from Bacillus mesentericus strain 76 . Biochemistry . 29 . 2 . 527–34 . January 1990 . 2302386 . 10.1021/bi00454a029 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bacillolysin".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.