Baccharis oxide synthase explained

Baccharis oxide synthase
Ec Number:5.4.99.51

Baccharis oxide synthase is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baccharis-oxide-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene

\rightleftharpoons

baccharis oxide

The enzyme from Stevia rebaudiana also gives traces of other triterpenoids.

Notes and References

  1. Shibuya M, Sagara A, Saitoh A, Kushiro T, Ebizuka Y . Biosynthesis of baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring . Organic Letters . 10 . 21 . 5071–4 . November 2008 . 18850716 . 10.1021/ol802072y .