Attacin Explained

Symbol:Attacin, Att
Attacin
Interpro:IPR040428

Attacin is a glycine-rich protein of about 20 kDa belonging to the group of antimicrobial peptides (AMP). It is active against Gram-negative bacteria.[1]

Attacin was first discovered in Hyalophora cecropia,[2] [3] but is widely conserved in different insects from butterflies to fruit flies.

See also

Notes and References

  1. Book: Imler JL, Bulet P . Mechanisms of Epithelial Defense . Antimicrobial Peptides in Drosophila: Structures,Activities and Gene Regulation . 86 . 1–21 . 2005 . 15976485 . 10.1159/000086648 . 978-3-8055-7862-2 . Chemical Immunology and Allergy .
  2. Hultmark D, Engström A, Andersson K, Steiner H, Bennich H, Boman HG . Insect immunity. Attacins, a family of antibacterial proteins from Hyalophora cecropia . The EMBO Journal . 2 . 4 . 571–6 . 1983 . 6628360 . 555063 . 10.1002/j.1460-2075.1983.tb01465.x .
  3. Lee JY, Edlund T, Ny T, Faye I, Boman HG . Insect immunity. Isolation of cDNA clones corresponding to attacins and immune protein P4 from Hyalophora cecropia . The EMBO Journal . 2 . 4 . 577–81 . 1983 . 6628361 . 555064 . 10.1002/j.1460-2075.1983.tb01466.x .

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