Atraric acid explained

Atraric acid is a naturally occurring phenolic compound and ester with the IUPAC name methyl 2,4-dihydroxy-3,6-dimethylbenzoate and molecular formula C₁₀H₁₂O₄.^[1] It occurs in the root-bark of Pygeum africanum^[2] and Evernia prunastri (Oakmoss). There is evidence to suggest that it has antiandrogenic activity in humans and its use in treatment of benign prostate hyperplasia, prostate cancer, and spinal and bulbar muscular atrophy has been investigated.

References

Other sources

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• Book: Watts' dictionary of chemistry Henry Watts, Henry Forster Morley, Matthew Moncrieff Pattison Muir . 361 . Watts . Henry . Morley . Henry Forster . Muir . Matthew Moncrieff Pattison . 1888 .
• Book: Alternative and Complementary Therapies for Cancer: Integrative Approaches . 489. 978-1-4419-0020-3 . Alaoui-Jamali . Moulay . 2 September 2010 . Springer .
• Stojanović . Igor . Niko S. Radulović . Tatjana Lj Mitrović . Slaviša M. Stamenković . Gordana S. Stojanović . Volatile Constituents of Parmeliaceae Lichens . 10 December 2010 . https://web.archive.org/web/20111006211320/http://www.doiserbia.nb.rs/img/doi/0352-5139/2011%20OnLine-First/0352-51391100087S.pdf . October 6, 2011. 10.2298/JSC101004087S. Journal of the Serbian Chemical Society. 76. 7. 987–994 .

Notes and References

1. US. 20090143466. application. Isolation of Atraric Acid, Synthesis of Atraric Acid Derivatives, and Use of Atraric Acid and the Derivatives Thereof for the Treatment of Benign Prostatic Hyperplasia, Prostate Carcinoma and Spinobulbar Muscular Atrophy. 2009-06-04. 2006-01-28. 2005-02-05. Aria Baniahmad. Hans-Rainer Hoffmann. Rudolf Matusch. Aria Baniahmad. Hans-Rainer Hoffmann, Rudolf Matusch.
2. Book: Buss, Antony. Natural Product Chemistry for Drug Discovery. 2010. Royal Society of Chemistry. 978-0-85404-193-0. 145, 146. Mark Butler.