Asterric acid explained

Asterric acid is a fungal metabolite that can inhibit endothelin binding,[1] [2] first isolated from Aspergillus terreus.[3] Its derivatives and similar phenolic fungal isolates are a subject of research on anti-angiogenic compounds.[4]

Notes and References

  1. 1473998 . 1992 . Ohashi . H . Akiyama . H . Nishikori . K . Mochizuki . J . Asterric acid, a new endothelin binding inhibitor . 45 . 10 . 1684–5 . The Journal of Antibiotics . 10.7164/antibiotics.45.1684. free .
  2. Yang . Xiao-Long . Zhang . Jing-Ze . Luo . Du-Qiang . 2012-06-01 . The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus . Natural Product Reports . en . 29 . 6 . 622–641 . 10.1039/C2NP00073C . 1460-4752.
  3. Curtis . R. F. . Hassall . C. H. . Jones . D. W. . Williams . T. W. . 1960-01-01 . 940. The biosynthesis of phenols. Part II. Asterric acid, a metabolic product of aspergillus terreus thom . Journal of the Chemical Society (Resumed) . en . 0 . 4838–4842 . 10.1039/JR9600004838 . 0368-1769.
  4. Lee . Hee Jung . Lee . Jeong Hyeong . Hwang . Bang Yeon . Kim . Hang Sub . Lee . Jung Joon . 2002 . Fungal Metabolites, Asterric Acid Derivatives Inhibit Vascular Endothelial Growth Factor (VEGF)-induced Tube Formation of HUVECs. . The Journal of Antibiotics . en . 55 . 6 . 552–556 . 10.7164/antibiotics.55.552 . 0021-8820. free .

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