Aspartyl aminopeptidase explained

Aspartyl aminopeptidase
Ec Number:3.4.11.21
Cas Number:9074-83-3
Width:270

Aspartyl aminopeptidase is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate

Aminoacyl-arylamides are poor substrates.

Notes and References

  1. Kelly JA, Neidle EL, Neidle A . An aminopeptidase from mouse brain cytosol that cleaves N-terminal acidic amino acid residues . Journal of Neurochemistry . 40 . 6 . 1727–34 . June 1983 . 6854330 . 10.1111/j.1471-4159.1983.tb08148.x . 25470156 .
  2. Wilk S, Wilk E, Magnusson RP . Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase . The Journal of Biological Chemistry . 273 . 26 . 15961–70 . June 1998 . 9632644 . 10.1074/jbc.273.26.15961 . free .