Aspartate N-acetyltransferase explained

aspartate N-acetyltransferase
Ec Number:	2.3.1.17
Cas Number:	9029-99-6
Go Code:	0017188

In enzymology, an aspartate N-acetyltransferase is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-aspartate

\rightleftharpoons CoA + N-acetyl-L-aspartate

Thus, the two substrates of this enzyme are acetyl-CoA and L-aspartate, whereas its two products are CoA and N-acetyl-L-aspartate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-aspartate N-acetyltransferase. Other names in common use include aspartate acetyltransferase, and L-aspartate N-acetyltransferase.

References

• Goldstein FB . 1959 . Biosynthesis of N-acetyl-L-aspartic acid . J. Biol. Chem. . 234 . 2702 - 2706 .
• Knizley H . The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder . The Journal of Biological Chemistry . 242 . 20 . 4619–22 . October 1967 . 6061408 .