Asparagusate reductase explained

asparagusate reductase
Ec Number:	1.8.1.11
Cas Number:	56126-52-4
Go Code:	0050445

Asparagusate reductase is an enzyme that catalyzes the chemical reaction

3-mercapto-2-mercaptomethylpropanoate + NAD⁺

\rightleftharpoons asparagusate + NADH + H⁺

Thus, the two substrates of this enzyme are 3-mercapto-2-mercaptomethylpropanoate and nicotinamide adenine dinucleotide ion, whereas its 3 products are asparagusate, nicotinamide adenine dinucleotide, and hydrogen ion.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase. Other names in common use include asparagusate dehydrogenase, asparagusic dehydrogenase, asparagusate reductase (NADH2), and NADH2:asparagusate oxidoreductase.

References

• Yanagawa H, Egami F . 1975 . Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria . Biochim. Biophys. Acta . 384 . 342 - 52 . 1125255 . 2 . 10.1016/0005-2744(75)90035-2.
• Yanagawa H, Egami F . 1976 . Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria. Physical, chemical, and enzymatic properties . J. Biol. Chem. . 251 . 3637 - 44 . 180003 . 12 .