Artesunate/mefloquine explained

Type:combo
Component1:Artesunate
Class1:artemisinin
Component2:Mefloquine
Class2:antimalarial
Cas Number:60473-87-2
Atc Prefix:P01
Atc Suffix:BF02

Artesunate/mefloquine is a medication used to treat malaria. It is a fixed dose combination of artesunate and mefloquine. Specifically it is recommended to treat uncomplicated falciparum malaria.[1] It is taken by mouth.

Side effects are similar to the medications being used separately.[1] Use is recommended as it decreases the possibility of either medications being used alone.[1] Dose forms appropriate for children are also available.[1]

Artesunate/mefloquine came into commercial use in 2008.[2] It is on the World Health Organization's List of Essential Medicines.[3] It is approved for medical use in Brazil, India, and Malaysia.[1] It is not commercially available in the United States.[4]

Medical uses

Artesunate/mefloquine is a recommended treatment in Southeast Asia while in Africa artesunate/amodiaquine, artemether/lumefantrine, artesunate/sulfadoxine/pyrimethamine are often preferred.[5]

See also

External links

Notes and References

  1. Book: ((World Health Organization)) . The Selection and Use of Essential Medicines: Report of the WHO Expert Committee, 2013 (including the 18th WHO Model List of Essential Medicines and the 4th WHO Model List of Essential Medicines for Children) . 2014. World Health Organization. 9789241209854. 43–4. 10665/112729 . free .
  2. Book: Staines HM, Krishna S . Sanjeev Krishna. Treatment and Prevention of Malaria: Antimalarial Drug Chemistry, Action and Use. 2012. Springer Science & Business Media. 9783034604802. 239. en. live. https://web.archive.org/web/20161220161905/https://books.google.ca/books?id=IXWOXUpylO8C&pg=PA239. 2016-12-20.
  3. Book: ((World Health Organization)) . World Health Organization model list of essential medicines: 21st list 2019 . 2019 . 10665/325771 . World Health Organization . World Health Organization . Geneva . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO . free .
  4. Book: Sanford CA, Jong EC, Pottinger PS . The Travel and Tropical Medicine Manual. 2016. Elsevier Health Sciences. 9780323417426. 307. 5. en. live. https://web.archive.org/web/20161220162041/https://books.google.ca/books?id=jyTRDAAAQBAJ&pg=PA307. 2016-12-20.
  5. Book: Marcondes CB . Arthropod Borne Diseases. 2016. Springer. 9783319138848. 35. en. live. https://web.archive.org/web/20161220163853/https://books.google.ca/books?id=Qs55DQAAQBAJ&pg=PA335. 2016-12-20.