Arsenate-mycothiol transferase explained

Arsenate-mycothiol transferase
Ec Number:	2.8.4.2

Arsenate-mycothiol transferase (ArsC1, ArsC2, mycothiol:arsenate transferase) is an enzyme with systematic name mycothiol:arsenate S-arsenotransferase.^[1] This enzyme catalyses the following chemical reaction

mycothiol + arsenate

\rightleftharpoons

arseno-mycothiol + H₂O

Reduction of arsenate is part of a defence mechanism of the cell against toxic arsenate.

Notes and References

Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J . Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange . The Journal of Biological Chemistry . 284 . 22 . 15107–16 . May 2009 . 19286650 . 2685692 . 10.1074/jbc.m900877200 . free .