Apudoma Explained

Apudoma
Field:	oncology

In pathology, an apudoma is an endocrine tumour that arises from an APUD cell^{[1] [2]} from structures such as the ampulla of Vater.^[3] They were historically thought to be derived from neural crest cells,^[4] but this has since been shown to be untrue (see neuroendocrine tumor).The term dates back to at least 1975.^[5] Because the label "apudoma" is very general, it is preferred to use a more specific term when possible.

See also

• VIPoma
• Carcinoid tumor

Notes and References

1. Welbourn RB . Current status of the apudomas . Ann. Surg. . 185 . 1 . 1–12 . 1977 . 12724 . 10.1097/00000658-197701000-00001 . 1396259. Full Free Text
2. Fukunaga Y, Hirata S, Tanimura S . Superficial undifferentiated small cell carcinoma of the esophagus showing an interesting growing pattern in histology . Hepatogastroenterology . 47 . 32 . 429–32 . 2000 . 10791205 . etal.
3. Galati G, Fiori E, Tiziano G . [Apudoma of Vater's ampulla: case report and review of the literature] . it . Il Giornale di Chirurgia . 23 . 3 . 97–100 . 2002 . 12109233 . etal.
4. Web site: eMedicine - VIPoma : Article by Robert J Ferry, Jr, MD . 2007-09-22 . https://web.archive.org/web/20070816095543/http://www.emedicine.com/ped/topic2428.htm. 16 August 2007 . live.
5. Spence RW, Burns-Cox CJ . ACTH-secreting 'apudoma' of gallbladder . Gut . 16 . 6 . 473–6 . 1975 . 168130 . 10.1136/gut.16.6.473 . 1411036.