Apoatropine Explained

Apoatropine (atropatropine) is a member of class of tropane alkaloids. Chemically, it is an ester formed from tropine and atropic acid. Apoatropine can be found in plants of family Solanaceae. It is a bitter crystalline alkaloid. Examples of related tropane alkaloids include atropine, hyoscyamine, and hyoscine. Though apoatropine is found in various plants, it can also be prepared by the dehydration of atropine using nitric acid . Apoatropine is used as a pigment.

Toxicity

It is said to be 20 times more toxic than atropine.[1]

Notes and References

  1. Krantz. J. C.. Forrest. J. W.. Heisse. C. K.. Contribution to the Pharmacology of Apoatropine and Its Methyl Bromide. Experimental Biology and Medicine. 86. 3. 1954. 511–512. 1535-3702. 10.3181/00379727-86-21150. 13194706 . 40304336 .