Anti-Jo1 Explained

Anti-Jo1 is an anti-nuclear antibody.^{[1] [2]}

Anti-Jo1 has been associated with inflammatory myopathies such as polymyositis, dermatomyositis and antisynthetase syndrome.^{[3] [4]}

It has histidine-tRNA ligase as a target.

Notes and References

1. Gutiérrez-Ramos R . Gonzalez-Díaz V . Pacheco-Tovar MG . López-Luna A . Avalos-Díaz E . Herrera-Esparza R . A dermatomyositis and scleroderma overlap syndrome with a remarkable high titer of anti-exosome antibodies . Reumatismo . 60 . 4 . 296–300 . 2008 . 19132155 . 10.4081/reumatismo.2008.296. free .
2. Zold E . Szodoray P . Gaal J . etal . Vitamin D deficiency in undifferentiated connective tissue disease . Arthritis Res. Ther. . 10 . 5 . R123 . 2008 . 18928561 . 2592813 . 10.1186/ar2533 . free .
3. Kalenian M . Zweiman B . Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association . Clinical and Diagnostic Laboratory Immunology . 4 . 2 . 236–40 . March 1997 . 9067664 . 170510 . 10.1128/CDLI.4.2.236-240.1997.
4. Web site: Antisynthetase syndrome . Orphanet . 20 March 2019.