Anthranilate 3-monooxygenase (FAD) explained

Anthranilate 3-monooxygenase (FAD)
Ec Number:	1.14.14.8

Anthranilate 3-monooxygenase (FAD) (anthranilate 3-hydroxylase, anthranilate hydroxylase) is an enzyme with systematic name anthranilate,FAD:oxygen oxidoreductase (3-hydroxylating).^[1] This enzyme catalyses the following chemical reaction

anthranilate + FADH₂ + O₂

\rightleftharpoons 3-hydroxyanthranilate + FAD + H₂O

The enzyme from the bacterium Geobacillus thermodenitrificans participates in tryptophan degradation.

Notes and References

1. Liu X, Dong Y, Li X, Ren Y, Li Y, Wang W, Wang L, Feng L . Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2 . Microbiology . 156 . Pt 2 . 589–95 . February 2010 . 19942660 . 10.1099/mic.0.031880-0 . free .