Androstanolone enanthate explained

Androstanolone enanthate (brand name Anaboleen Depot), also known as stanolone enanthate or dihydrotestosterone heptanoate (DHTH), as well as 5α-androstan-17β-ol-3-one 17β-heptanoate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester.[1] [2]  It is used as an injectable and acts as a prodrug of androstanolone (stanolone, dihydrotestosterone, DHT). The drug has been studied in and found to be effective in the treatment of gynecomastia in boys and adult men.[3] [4] [5]  The pharmacology of androstanolone enanthate has been studied.[6] [7]


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Notes and References


  1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 640–.
    2. 

  2. Book: Morton IK, Hall JM . Concise Dictionary of Pharmacological Agents: Properties and Synonyms. 6 December 2012. Springer Science & Business Media. 978-94-011-4439-1. 261–.
    3. 

  3. Swerdloff RS, Wang C . Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent . Bailliere's Clinical Endocrinology and Metabolism . 12 . 3 . 501–506 . October 1998 . 10332569 . 10.1016/S0950-351X(98)80267-X .
    4. 

  4. Eberle AJ, Sparrow JT, Keenan BS . Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate . The Journal of Pediatrics . 109 . 1 . 144–149 . July 1986 . 3088241 . 10.1016/s0022-3476(86)80596-0 .
    5. 

  5. Swerdloff RS, Dudley RE, Page ST, Wang C, Salameh WA . Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels . Endocrine Reviews . 38 . 3 . 220–254 . June 2017 . 28472278 . 6459338 . 10.1210/er.2016-1067 . free .
    6. 

  6. Keenan BS, Eberle AJ, Sparrow JT, Greger NG, Panko WB . Dihydrotestosterone heptanoate: synthesis, pharmacokinetics, and effects on hypothalamic-pituitary-testicular function . The Journal of Clinical Endocrinology and Metabolism . 64 . 3 . 557–562 . March 1987 . 3546348 . 10.1210/jcem-64-3-557 .
    7. 

  7. Coutts SB, Kicman AT, Hurst DT, Cowan DA . Intramuscular administration of 5 alpha-dihydrotestosterone heptanoate: changes in urinary hormone profile . Clinical Chemistry . 43 . 11 . 2091–2098 . November 1997 . 9365393 . 10.1093/clinchem/43.11.2091 . free .
    8. 



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