Aminosteroid Explained

Aminosteroids are a group of steroids with a similar structure based on an amino-substituted steroid nucleus.[1] [2] They are neuromuscular blocking agents, acting as competitive antagonists of the nicotinic acetylcholine receptor (nAChR), and block the signaling of acetylcholine in the nervous system.[3] These drugs include candocuronium iodide (chandonium iodide), dacuronium bromide, dihydrochandonium, dipyrandium, malouetine, pancuronium bromide, pipecuronium bromide, rapacuronium bromide, rocuronium bromide, stercuronium iodide, and vecuronium bromide.[4]

See also

Notes and References

  1. Book: Ted Lin. Tim Smith. Colin Pinnock. Fundamentals of Anaesthesia. 1 December 2016. Cambridge University Press. 978-1-316-66678-4. 650–.
  2. Book: Thomas L. Lemke. David A. Williams. Foye's Principles of Medicinal Chemistry. 24 January 2012. Lippincott Williams & Wilkins. 978-1-60913-345-0. 336–337.
  3. Book: Alexandra Dugdale. Veterinary Anaesthesia: Principles to Practice. 28 November 2011. John Wiley & Sons. 978-1-118-27933-5. 144–.
  4. Web site: Reference at www.who.int.