Amine oxidase explained

An amine oxidase is an enzyme that catalyzes the oxidative cleavage of alkylamines into aldehydes and ammonia:^[1]

RCH₂NH₂ + H₂O + O₂

\rightleftharpoons RCHO + NH₃ + H₂O₂

Amine oxidases are divided into two subfamilies based on the cofactor they contain:

Class	Cofactor	Subclass	Enzyme Commission number	Human genes
Amine oxidase (formerly)	copper			LOX
				AOC2, AOC3
				AOC1
	flavin	N/A

Notes and References

1. Book: Mondovì B, Finazzi Agrò A . Structure and Function Relationships in Biochemical Systems . Structure and Function of Amine Oxidases . Advances in Experimental Medicine and Biology . 148 . 141–53 . 1982 . 7124512 . 10.1007/978-1-4615-9281-5_12 . 978-1-4615-9283-9 .