Amadinone Explained

Amadinone (INN), also known as 19-norchlormadinone, is a steroidal progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups that was synthesized and characterized in 1968 but was never marketed.^{[1] [2]} It has antigonadotropic properties, and for this reason, is a functional antiandrogen.^{[3] [4]} An acetate ester, amadinone acetate, also exists, but similarly was never marketed.

See also

• Chlormadinone
• Chlormadinone acetate

Notes and References

1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . 14 November 2014 . Springer . 978-1-4757-2085-3 . 35–.
2. Book: William Andrew Publishing . Pharmaceutical Manufacturing Encyclopedia, 3rd Edition . 22 October 2013 . Elsevier . 978-0-8155-1856-3 . 206–.
3. Book: Hughes A, Hasan SH, Oertel GW, Voss HE, Bahner F, Neumann G, Steinbeck H, Gräf KJ, Brotherton J, Horn HJ, Wagner RK . Androgens II and Antiandrogens / Androgene II und Antiandrogene . 27 November 2013 . Springer Science & Business Media . 978-3-642-80859-3 . 495–.
4. Kent JR, Hill M, Huix FJ, Segre EJ . Seminal acid phosphatase content in the clinical bioassay of androgens and antiandrogens . Clinical Pharmacology and Therapeutics . 13 . 2 . 205–11 . 1972 . 5017374 . 10.1002/cpt1972132205 . 40886901 .